Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6813135 | 0.90 | MMP1 (0.67) | MMP1FFAR1NR3C1RORCCETP | |
| SCHEMBL6813259 | 0.89 | MMP1 (0.59) | MMP1SMN1; SMN2FFAR1NR3C1RORC | |
| SCHEMBL6809653 | 0.88 | MMP1 (0.62) | MMP1SMN1; SMN2FFAR1NR3C1CETP | |
| SCHEMBL6689521 | 0.87 | MMP1 (0.61) | MMP1SMN1; SMN2FFAR1NR3C1RORC | |
| SCHEMBL6809611 | 0.86 | MMP1 (0.54) | MMP1SMN1; SMN2FFAR1NR3C1RORC | |
| SCHEMBL6689128 | 0.86 | MMP1 (0.65) | MMP1SMN1; SMN2FFAR1NR3C1CETP | |
| SCHEMBL4616532 | 0.85 | MMP1 (0.49) | MMP1RORCKMT2ATDP1 | |
| SCHEMBL6870847 | 0.85 | MMP1 (0.55) | MMP1SMN1; SMN2FFAR1CETPNPSR1 | |
| SCHEMBL6862342 | 0.85 | MMP1 (0.59) | MMP1SMN1; SMN2FFAR1CETPNPSR1 | |
| SCHEMBL6813091 | 0.83 | MMP1 (0.76) | MMP1SMN1; SMN2FFAR1CETPLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1415984-A1 | Aryloxyarylsulfonylamino hydroxamic acid derivatives | Pfizer Products Inc. (US) | 2004-05-06 | — | — | EP | disclosed |
| EP-1003720-B1 | ARYLOXYARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER PROD INC (US) | 2004-03-31 | — | — | EP | disclosed |
| US-6214872-B1 | ANTIARTHRITIC AND ANTICARCINOGENIC AGENTS | PFIZER INC. | 2001-04-10 | — | — | US | disclosed |
| EP-1003720-A1 | ARYLOXYARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | Pfizer Products Inc. (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999007675-A1 | ARYLOXYARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER PRODUCTS INC. (US) | 1999-02-18 | — | — | WO | disclosed |