Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 6/20 | 0.59 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689521 | 0.98 | MMP1 (0.61) | MMP1CETPSMN1; SMN2LTA4HFFAR1 | |
| SCHEMBL6813465 | 0.89 | MMP1 (0.55) | MMP1CETPSMN1; SMN2LTA4HFFAR1 | |
| SCHEMBL4614179 | 0.86 | MMP1 (0.51) | MMP1RORCNPSR1KMT2AALDH1A1 | |
| SCHEMBL6813091 | 0.86 | MMP1 (0.76) | MMP1CETPSMN1; SMN2LTA4HFFAR1 | |
| SCHEMBL6809653 | 0.85 | MMP1 (0.62) | MMP1CETPSMN1; SMN2LTA4HFFAR1 | |
| SCHEMBL6691684 | 0.84 | MMP1 (0.79) | MMP1CETPSMN1; SMN2LTA4HFFAR1 | |
| SCHEMBL6689128 | 0.83 | MMP1 (0.65) | MMP1CETPSMN1; SMN2LTA4HFFAR1 | |
| SCHEMBL6862342 | 0.82 | MMP1 (0.59) | MMP1CETPSMN1; SMN2LTA4HFFAR1 | |
| SCHEMBL6693057 | 0.81 | MMP1 (0.68) | MMP1LTA4HMMP13 | |
| SCHEMBL6813135 | 0.81 | MMP1 (0.67) | MMP1CETPLTA4HFFAR1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1415984-A1 | Aryloxyarylsulfonylamino hydroxamic acid derivatives | Pfizer Products Inc. (US) | 2004-05-06 | — | — | EP | disclosed |
| EP-1003720-B1 | ARYLOXYARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER PROD INC (US) | 2004-03-31 | — | — | EP | disclosed |
| US-6214872-B1 | ANTIARTHRITIC AND ANTICARCINOGENIC AGENTS | PFIZER INC. | 2001-04-10 | — | — | US | disclosed |