SCHEMBL6813499

SCHEMBL6813499

O=C([O-])[C@@](O)(Cl)[C@@H](O)[C@H](O)[C@H](O)CO.O=C([O-])[C@@](O)(Cl)[C@@H](O)[C@H](O)[C@H](O)CO.[Sn+2]

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.37
PDE4A P27815 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
USP2 O75604 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
KDM4E B2RXH2 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29879125 0.80 PDE4A (0.43) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL6817366 0.80 PDE4A (0.43) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL8967965 0.76 LMNA (0.50) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL31542046 0.76 LMNA (0.36) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL11870178 0.74 LMNA (0.44) LMNAL3MBTL1PDE4ATDP1USP2
Zinc Ion SCHEMBL14920928 0.74 LMNA (0.44) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL6129267 0.74 LMNA (0.40) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL11501996 0.73 LMNA (0.47) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL6668472 0.73 LMNA (0.47) LMNAL3MBTL1PDE4ATDP1USP2
Potassium Ion SCHEMBL11501588 0.73 LMNA (0.42) LMNAL3MBTL1PDE4ATDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1227789-B1 IMPROVED DUAL PHASE STANNOUS ORAL COMPOSITIONS PROCTER & GAMBLE (US) 2004-09-22 EP claimed
US-6521216-B1 Dentifrices comprising mixtures of stannous fluoride, chloride and sodium gluconate used as microbiocides and to prevent oral diseases and plaque THE PROCTER & GAMBLE COMPANY 2003-02-18 US claimed
EP-1227789-A1 IMPROVED DUAL PHASE STANNOUS ORAL COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2002-08-07 EP claimed
WO-2001034109-A1 IMPROVED DUAL PHASE STANNOUS ORAL COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2001-05-17 WO claimed
EP-1227789-B1 IMPROVED DUAL PHASE STANNOUS ORAL COMPOSITIONS PROCTER & GAMBLE (US) 2004-09-22 EP disclosed
EP-1227789-B1 IMPROVED DUAL PHASE STANNOUS ORAL COMPOSITIONS PROCTER & GAMBLE (US) 2004-09-22 EP disclosed
US-6521216-B1 Dentifrices comprising mixtures of stannous fluoride, chloride and sodium gluconate used as microbiocides and to prevent oral diseases and plaque THE PROCTER & GAMBLE COMPANY 2003-02-18 US disclosed
US-6521216-B1 Dentifrices comprising mixtures of stannous fluoride, chloride and sodium gluconate used as microbiocides and to prevent oral diseases and plaque THE PROCTER & GAMBLE COMPANY 2003-02-18 US disclosed
EP-1227789-A1 IMPROVED DUAL PHASE STANNOUS ORAL COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2002-08-07 EP disclosed
EP-1227789-A1 IMPROVED DUAL PHASE STANNOUS ORAL COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2002-08-07 EP disclosed
WO-2001034109-A1 IMPROVED DUAL PHASE STANNOUS ORAL COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2001-05-17 WO disclosed
WO-2001034109-A1 IMPROVED DUAL PHASE STANNOUS ORAL COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2001-05-17 WO disclosed