Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11501996 | 0.96 | LMNA (0.47) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL8967965 | 0.76 | LMNA (0.50) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL11870178 | 0.74 | LMNA (0.44) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| Zinc Ion SCHEMBL14920928 | 0.74 | LMNA (0.44) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| Potassium Ion SCHEMBL9419063 | 0.74 | LMNA (0.40) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL2771694 | 0.74 | LMNA (0.40) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL6668472 | 0.73 | LMNA (0.47) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL6813499 | 0.73 | LMNA (0.42) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| Potassium Ion SCHEMBL11864917 | 0.72 | LMNA (0.38) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL8968603 | 0.71 | LMNA (0.53) | LMNAL3MBTL1PDE4ATDP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162205-A | Method of electroplating tin and alkaline electroplating bath therefor | VULCAN MATERIALS COMPANY (US) | 1979-07-24 | — | — | US | disclosed |