Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | BCL6 | P41182 | 3/20 | 0.49 |
| ▸ | BCOR | Q6W2J9 | 3/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.44 |
| ▸ | RET | P07949 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | GSK3A | P49840 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6813310 | 0.86 | PTK6 (0.49) | MEN1KMT2AMAPTBCL6BCOR | |
| SCHEMBL6813639 | 0.81 | PRKD3 (0.50) | MEN1KMT2AMAPTPRKD3MAP4K4 | |
| SCHEMBL6818052 | 0.80 | PRKD3 (0.49) | MEN1KMT2AMAPTDHFRPRKD3 | |
| SCHEMBL6813313 | 0.80 | PRKD3 (0.49) | MEN1KMT2AMAPTL3MBTL1PRKD3 | |
| SCHEMBL6392629 | 0.80 | PRKD3 (0.62) | MEN1KMT2AMAPTDHFRPRKD3 | |
| SCHEMBL20569889 | 0.79 | PRKD3 (0.54) | MEN1KMT2AMAPTAPEX1HTT | |
| SCHEMBL6810839 | 0.77 | PDE3B (0.45) | MEN1KMT2AMAPTAPEX1HTT | |
| SCHEMBL6810523 | 0.77 | HSPB1 (0.44) | MEN1KMT2AMAPTAPEX1HTT | |
| SCHEMBL6392438 | 0.77 | PDE3B (0.47) | KMT2APRKD3MAP4K4RETPIM1 | |
| SCHEMBL6813333 | 0.77 | BCL6 (0.48) | MEN1KMT2AMAPTBCL6BCOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017384-B1 | AZABENZIMIDAZOLE-BASED COMPOUNDS FOR MODULATING SERINE/THREONINE PROTEIN KINASE FUNCTION | ZENTARIS GMBH (DE) | 2004-11-10 | — | — | EP | disclosed |