Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 2/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | LDHB | P07195 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6813649 | 0.90 | KDM5A (0.36) | KDM5AKDM5BP2RY14CYP17A1KDM4E | |
| SCHEMBL6476575 | 0.90 | KDM5A (0.40) | KDM5AKDM5BP2RY14KDM4CALDH1A1 | |
| SCHEMBL6813648 | 0.82 | NAMPT (0.39) | ALDH1A1PDE2A | |
| SCHEMBL6478088 | 0.77 | PTGER4 (0.41) | KDM4EALDH1A1 | |
| Niacinamide SCHEMBL6818598 | 0.72 | FYN (0.39) | FYNP2RY14VNN1KDM4EMEN1 | |
| SCHEMBL6489375 | 0.71 | GRM4 (0.33) | KDM5AKDM5BMPO | |
| SCHEMBL6485426 | 0.71 | P2RY14 (0.36) | FYNKDM5AKDM5BP2RY14PARP1 | |
| SCHEMBL6289368 | 0.71 | KDM5A (0.38) | KDM5AKDM5BP2RY14LDHALDHB | |
| SCHEMBL6490897 | 0.70 | KDM5A (0.38) | FYNKDM5AKDM5BP2RY14MEN1 | |
| SCHEMBL6819189 | 0.66 | KDM5A (0.37) | FYNKDM5AKDM5BP2RY14KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014908-A1 | HETEROBICYLCIC METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | claimed |