Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Picolamine SCHEMBL6818607 | 0.89 | PLA2G7 (0.34) | ALDH1A1CACNA1GCACNA1HCACNA1IPLA2G7 | |
| SCHEMBL6485426 | 0.88 | P2RY14 (0.36) | FYNPARP1CACNA1GCACNA1HCACNA1I | |
| SCHEMBL6818605 | 0.82 | ALDH1A1 (0.42) | CYP1A2ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL6477100 | 0.77 | CHRM4 (0.43) | CACNA1GCACNA1HCACNA1IMAPT | |
| SCHEMBL6813645 | 0.72 | FYN (0.36) | FYNALDH1A1PARP1P2RY14KDM4E | |
| SCHEMBL6818812 | 0.70 | CHRM4 (0.37) | CACNA1GCACNA1HCACNA1IPOLBMAPT | |
| SCHEMBL6814142 | 0.69 | KDM5A (0.35) | FYNP2RY14MAPT | |
| SCHEMBL6484565 | 0.69 | RXRA (0.35) | ALDH1A1P2RY14MAPTMAPK1 | |
| SCHEMBL6476575 | 0.67 | KDM5A (0.40) | ALDH1A1PARP1CACNA1HP2RY14TSHR | |
| SCHEMBL6813649 | 0.66 | KDM5A (0.36) | ALDH1A1P2RY14KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014908-A1 | HETEROBICYLCIC METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |