Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.37 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPK7 | Q13164 | 3/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6478088 | 0.92 | PTGER4 (0.41) | ALDH1A1HPGDCACNA1GCACNA1HCACNA1I | |
| SCHEMBL6813649 | 0.84 | KDM5A (0.36) | ALDH1A1PDE2A | |
| SCHEMBL6476575 | 0.83 | KDM5A (0.40) | ALDH1A1CACNA1HL3MBTL1PDE2A | |
| SCHEMBL6813645 | 0.82 | FYN (0.36) | ALDH1A1PDE2A | |
| SCHEMBL6289023 | 0.74 | CNR2 (0.41) | HPGDCACNA1GCACNA1HCACNA1IMMP13 | |
| SCHEMBL6484781 | 0.73 | PTGER4 (0.41) | ALDH1A1LMNAHPGDCACNA1GCACNA1H | |
| SCHEMBL6477100 | 0.73 | CHRM4 (0.43) | CACNA1GCACNA1HCACNA1I | |
| SCHEMBL6477648 | 0.73 | POLB (0.42) | SMN1; SMN2ALDH1A1HPGDMAPK1CACNA1G | |
| SCHEMBL6819154 | 0.71 | PTGER4 (0.41) | ALDH1A1LMNAHPGDCACNA1GCACNA1H | |
| SCHEMBL6818605 | 0.71 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1LMNAHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014908-A1 | HETEROBICYLCIC METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | claimed |