Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | CASR | P41180 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6813895 | 0.89 | CYP4F2 (0.49) | CYP2D6ADRB2SLC6A2SLC6A4CASR | |
| SCHEMBL6818076 | 0.84 | CYP2D6 (0.42) | CYP2D6ADRB2SLC6A2SLC6A4CASR | |
| SCHEMBL6813642 | 0.83 | ESR1 (0.52) | HSD17B10ALDH1A1ABCB1PPARGPPARA | |
| SCHEMBL6813693 | 0.82 | ALDH1A1 (0.48) | ALDH1A1ABCB1PPARGPPARA | |
| SCHEMBL6813752 | 0.82 | ALDH1A1 (0.45) | HSD17B10ALDH1A1ABCB1PPARGPPARA | |
| SCHEMBL15074081 | 0.82 | POLB (0.48) | NPC1RAB9AHSD17B10TP53ALDH1A1 | |
| SCHEMBL6813613 | 0.82 | GAA (0.50) | CYP2D6NPC1RAB9AHSD17B10ALDH1A1 | |
| SCHEMBL6813807 | 0.82 | ESR1 (0.48) | HSD17B10ALDH1A1ABCB1PPARGPPARA | |
| SCHEMBL14026553 | 0.82 | NPC1 (0.50) | NPC1RAB9AHSD17B10TP53ALDH1A1 | |
| SCHEMBL6818105 | 0.81 | ADRB3 (0.57) | HSD17B10ALDH1A1ABCB1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095932-B1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6538152-B1 | Obesity, hyperglycemia, urinary incontinence, intestinal or biliary calculi hypermotility, pollakiuria and depression treatment | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2003-03-25 | — | — | US | disclosed |
| EP-1095932-A1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2001-05-02 | — | — | EP | disclosed |