Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CASP9 | P55211 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6813642 | 0.88 | ESR1 (0.52) | ALDH1A1ABCB1PPARGPPARAHPGD | |
| SCHEMBL6813613 | 0.86 | GAA (0.50) | ALDH1A1ABCB1PPARGPPARAHSD17B10 | |
| SCHEMBL6813807 | 0.86 | ESR1 (0.48) | ALDH1A1ABCB1PPARGPPARAHPGD | |
| SCHEMBL6813693 | 0.86 | ALDH1A1 (0.48) | ALDH1A1ABCB1PPARGPPARAMEN1 | |
| SCHEMBL6818105 | 0.85 | ADRB3 (0.57) | ALDH1A1ABCB1PPARGPPARAMAPK1 | |
| SCHEMBL6814448 | 0.85 | ALDH1A1 (0.44) | ALDH1A1ABCB1PPARGPPARAADRB3 | |
| SCHEMBL14526124 | 0.85 | ALDH1A1 (0.48) | ALDH1A1ABCB1MAPK1HPGDNPSR1 | |
| SCHEMBL25194428 | 0.83 | ALDH1A1 (0.48) | ALDH1A1ABCB1MAPK1HPGDNPSR1 | |
| SCHEMBL6814065 | 0.83 | ABCB1 (0.47) | ALDH1A1ABCB1PPARGPPARAMAPK1 | |
| SCHEMBL6813655 | 0.82 | CYP2D6 (0.44) | ALDH1A1ABCB1PPARGPPARAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095932-B1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6538152-B1 | Obesity, hyperglycemia, urinary incontinence, intestinal or biliary calculi hypermotility, pollakiuria and depression treatment | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2003-03-25 | — | — | US | disclosed |
| EP-1095932-A1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2001-05-02 | — | — | EP | disclosed |