Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 13/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694916 | 0.82 | PTGER4 (0.36) | — | |
| SCHEMBL6813762 | 0.81 | MMP13 (0.41) | MMP13LMNASMN1; SMN2SLC22A8 | |
| SCHEMBL6696589 | 0.76 | MMP13 (0.56) | MMP13LMNAHPGDSMN1; SMN2 | |
| SCHEMBL6289361 | 0.67 | MAPK1 (0.38) | MMP13SLC22A8 | |
| SCHEMBL6694969 | 0.65 | MAPK1 (0.38) | MMP13SLC22A8 | |
| SCHEMBL6698262 | 0.65 | MMP13 (0.57) | MMP13SLC22A8 | |
| SCHEMBL6706893 | 0.64 | MAPK1 (0.45) | MMP13SLC22A8 | |
| SCHEMBL6703411 | 0.63 | MMP13 (0.56) | MMP13LMNASMN1; SMN2 | |
| SCHEMBL6912473 | 0.63 | MMP13 (0.38) | MMP13SLC22A8 | |
| SCHEMBL6701193 | 0.61 | MMP13 (0.64) | MMP13LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014916-A1 | PYRIMIDINE FUSED BICYCLIC METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |