Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6812441 | 0.89 | FOLH1 (0.53) | FOLH1FFAR4BRD4FFAR1LRRK2 | |
| SCHEMBL27820729 | 0.84 | FOLH1 (0.56) | FOLH1FFAR4FFAR1LRRK2APP | |
| SCHEMBL12726937 | 0.80 | TRPM8 (0.58) | BRD4ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL13643136 | 0.79 | FOLH1 (0.48) | FOLH1FFAR4BRD4LRRK2APP | |
| SCHEMBL14870834 | 0.79 | FOLH1 (0.48) | FOLH1FFAR4BRD4LRRK2APP | |
| SCHEMBL6810024 | 0.78 | ABCB1 (0.46) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1646958 | 0.78 | LRRK2 (0.63) | FOLH1BRD4LRRK2KDM4EALDH1A1 | |
| SCHEMBL10214905 | 0.78 | FOLH1 (0.47) | FOLH1FFAR4BRD4LRRK2APP | |
| SCHEMBL2617285 | 0.78 | FOLH1 (0.47) | FOLH1FFAR4BRD4LRRK2APP | |
| SCHEMBL6814409 | 0.78 | KDM4E (0.54) | FOLH1BRD4LRRK2APPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095932-B1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6538152-B1 | Obesity, hyperglycemia, urinary incontinence, intestinal or biliary calculi hypermotility, pollakiuria and depression treatment | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2003-03-25 | — | — | US | disclosed |
| EP-1095932-A1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2001-05-02 | — | — | EP | disclosed |