Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 5/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809773 | 0.85 | KDM4E (0.71) | KDM4EALDH1A1L3MBTL1POLBAPP | |
| SCHEMBL6813826 | 0.85 | ALDH1A1 (0.56) | KDM4EALDH1A1L3MBTL1POLBAPP | |
| SCHEMBL12726937 | 0.80 | TRPM8 (0.58) | ALDH1A1L3MBTL1BRD4LMNAMAPT | |
| SCHEMBL6812441 | 0.79 | FOLH1 (0.53) | KDM4EALDH1A1L3MBTL1POLBAPP | |
| SCHEMBL31056340 | 0.78 | APP (0.58) | KDM4EALDH1A1L3MBTL1POLBAPP | |
| SCHEMBL2932061 | 0.78 | ALDH1A1 (0.52) | KDM4EALDH1A1L3MBTL1POLBAPP | |
| SCHEMBL6813893 | 0.78 | FOLH1 (0.55) | KDM4EALDH1A1L3MBTL1POLBAPP | |
| SCHEMBL6546267 | 0.76 | POLB (0.57) | KDM4EALDH1A1L3MBTL1POLBAPP | |
| SCHEMBL18176240 | 0.76 | FFAR4 (0.52) | KDM4EALDH1A1L3MBTL1POLBAPP | |
| SCHEMBL1646958 | 0.75 | LRRK2 (0.63) | KDM4EALDH1A1L3MBTL1POLBBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095932-B1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6538152-B1 | Obesity, hyperglycemia, urinary incontinence, intestinal or biliary calculi hypermotility, pollakiuria and depression treatment | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2003-03-25 | — | — | US | disclosed |
| EP-1095932-A1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2001-05-02 | — | — | EP | disclosed |