Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6484092 | 0.91 | MEN1 (0.38) | MEN1KMT2AFPR1GRM4 | |
| SCHEMBL6475676 | 0.90 | MEN1 (0.39) | MEN1KMT2AFPR1TP53GRM4 | |
| SCHEMBL6490898 | 0.80 | TSHR (0.37) | MEN1KMT2AFPR1 | |
| SCHEMBL6488680 | 0.79 | TSHR (0.38) | MEN1KMT2AFPR1 | |
| SCHEMBL6484773 | 0.71 | MEN1 (0.41) | MEN1KMT2AFPR1TP53 | |
| SCHEMBL6476602 | 0.71 | FPR1 (0.44) | MEN1KMT2AFPR1 | |
| SCHEMBL6475923 | 0.70 | MAPT (0.46) | MEN1KMT2ATP53 | |
| SCHEMBL6486582 | 0.70 | MAPT (0.46) | MEN1KMT2ATP53 | |
| SCHEMBL6919813 | 0.67 | PTGER4 (0.45) | TP53 | |
| SCHEMBL6814009 | 0.66 | PTGER4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014908-A1 | HETEROBICYLCIC METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |