Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL9382950 | 0.77 | SLC7A5 (0.62) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| Valine SCHEMBL723520 | 0.77 | SLC7A5 (0.62) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL319023 | 0.76 | CA1 (0.32) | — | |
| Valine SCHEMBL8575925 | 0.75 | SLC7A5 (0.65) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| Hydrogen Sulfide SCHEMBL29272235 | 0.74 | CA1 (0.30) | — | |
| Valine SCHEMBL30591962 | 0.73 | SLC7A5 (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| Valine SCHEMBL30592077 | 0.73 | SLC7A5 (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| Valine SCHEMBL9088823 | 0.72 | SLC7A5 (0.75) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| Valine SCHEMBL9672476 | 0.72 | SLC7A5 (0.75) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| Valine SCHEMBL547430 | 0.72 | SLC7A5 (0.75) | SLC7A5SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115687-B1 | 5,6-DIHYDRONAPHTHALENYL DERIVATIVES HAVING RETINOID-LIKE ACTIVITY | BRISTOL MYERS SQUIBB CO (US) | 2004-05-26 | — | — | EP | disclosed |
| EP-1115687-A4 | 5,6-DIHYDRONAPHTHALENYL DERIVATIVES HAVING RETINOID-LIKE ACTIVITY | BRISTOL MYERS SQUIBB CO (US) | 2002-06-05 | — | — | EP | disclosed |
| EP-1115687-A1 | 5,6-DIHYDRONAPHTHALENYL DERIVATIVES HAVING RETINOID-LIKE ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-07-18 | — | — | EP | disclosed |
| US-6194601-B1 | USEFUL IN TREATMENT OF SKIN DISORDERS SUCH AS ACNE AND DAMAGE FROM AGE OR IRRADIATION; CHRONIC SKIN INFLAMMATORY INFLAMMATORY DISEASES SUCH AS PSORIASIS AND ATOPIC DERMATITIS; ANTITUMOR AGENTS FOR BREAST CANCER, LUNG CANCER; NONTOXIC | BRISTOL-MYERS SQUIBB COMPANY | 2001-02-27 | — | — | US | disclosed |
| WO-2000017147-A1 | 5,6-DIHYDRONAPHTHALENYL DERIVATIVES HAVING RETINOID-LIKE ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-03-30 | — | — | WO | disclosed |