Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.65 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.32 |
| ▸ | GABRE | P78334 | 2/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.32 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.32 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL9672476 | 0.84 | SLC7A5 (0.75) | SLC7A5SLC1A3SLC1A2SLC1A1GABRP | |
| Valine SCHEMBL9088823 | 0.84 | SLC7A5 (0.75) | SLC7A5SLC1A3SLC1A2SLC1A1GABRP | |
| Valine SCHEMBL547430 | 0.84 | SLC7A5 (0.75) | SLC7A5SLC1A3SLC1A2SLC1A1GABRP | |
| Valine SCHEMBL6360907 | 0.82 | SLC7A5 (0.71) | SLC7A5SLC1A3SLC1A2SLC1A1GABRP | |
| Valine SCHEMBL28052863 | 0.82 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| Valine SCHEMBL3076649 | 0.81 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1GABRP | |
| Valine SCHEMBL3486854 | 0.81 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1GABRP | |
| Valine SCHEMBL229818 | 0.81 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1GABRP | |
| Valine SCHEMBL2017287 | 0.81 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1GABRP | |
| Valine SCHEMBL20981544 | 0.81 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808058-A | Process for the preparation of 10-OXO-10, 11-dihydro-5H-dibenz (b,f) azepin-5-carboxamide | TRIFARMA S.R.L. (IT) | 1998-09-15 | — | — | US | disclosed |
| EP-0847390-A1 | A PROCESS FOR THE PREPARATION OF 10-OXO-10,11-DIHYDRO-5H-DIBENZ(b,f)AZEPIN-5-CARBOXAMIDE | TRIFARMA, S.R.L. (IT) | 1998-06-17 | — | — | EP | disclosed |
| WO-1996021649-A1 | A PROCESS FOR THE PREPARATION OF 10-OXO-10,11-DIHYDRO-5H-DIBENZ(b,f)AZEPIN-5-CARBOXAMIDE | TRIFARMA, S.R.L. (IT) | 1996-07-18 | — | — | WO | disclosed |
| US-5247071-A | Coupling diazonium salt with hydroxyalkylaniline derivative; etherification with a vinyl ether | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-21 | — | — | US | disclosed |