Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818985 | 0.92 | POLB (0.46) | SMN1; SMN2POLBALDH1A1TDP1KDM4E | |
| SCHEMBL6815906 | 0.89 | ALDH1A1 (0.44) | SMN1; SMN2POLBALDH1A1KDM4EMAPT | |
| SCHEMBL6819495 | 0.86 | CA1 (0.45) | SMN1; SMN2ALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL7161462 | 0.83 | KMT2A (0.40) | SMN1; SMN2POLBALDH1A1TDP1MAPT | |
| SCHEMBL6815974 | 0.82 | ALDH1A1 (0.44) | SMN1; SMN2POLBALDH1A1GAAKDM4E | |
| SCHEMBL6814849 | 0.82 | CYP1A2 (0.43) | SMN1; SMN2ALDH1A1TDP1MAPTHPGD | |
| SCHEMBL6815618 | 0.81 | CA1 (0.37) | SMN1; SMN2POLBMEN1KMT2ACA1 | |
| SCHEMBL6819435 | 0.81 | ALDH1A1 (0.55) | POLBALDH1A1GAAKDM4EMAPT | |
| SCHEMBL6814926 | 0.80 | POLB (0.63) | SMN1; SMN2POLBALDH1A1GAATDP1 | |
| SCHEMBL6819694 | 0.80 | ALDH1A1 (0.56) | POLBALDH1A1GAAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137632-B1 | THIOUREA INHIBITORS OF HERPES VIRUSES | WYETH CORP (US) | 2004-07-28 | — | — | EP | disclosed |