Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814933 | 0.89 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2POLBHTTMEN1 | |
| SCHEMBL6819495 | 0.88 | CA1 (0.45) | ALDH1A1L3MBTL1SMN1; SMN2HTTMEN1 | |
| SCHEMBL6818985 | 0.87 | POLB (0.46) | ALDH1A1SMN1; SMN2POLBHTTMEN1 | |
| SCHEMBL7161462 | 0.85 | KMT2A (0.40) | ALDH1A1L3MBTL1SMN1; SMN2POLBHTT | |
| SCHEMBL6814570 | 0.85 | LMNA (0.41) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL6819435 | 0.82 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1POLBHTTMEN1 | |
| SCHEMBL6814422 | 0.82 | CA1 (0.41) | ALDH1A1L3MBTL1SMN1; SMN2POLBMEN1 | |
| SCHEMBL6819694 | 0.81 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1POLBHTTMEN1 | |
| SCHEMBL6814849 | 0.81 | CYP1A2 (0.43) | ALDH1A1L3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6815618 | 0.81 | CA1 (0.37) | SMN1; SMN2POLBMEN1KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137632-B1 | THIOUREA INHIBITORS OF HERPES VIRUSES | WYETH CORP (US) | 2004-07-28 | — | — | EP | disclosed |