Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.59 |
| ▸ | PLG | P00747 | 3/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.59 |
| ▸ | PLAT | P00750 | 1/20 | 0.59 |
| ▸ | F2 | P00734 | 2/20 | 0.56 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.52 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7387778 | 1.00 | F10 (0.59) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL7387783 | 1.00 | F10 (0.59) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL7383597 | 0.95 | GPR119 (0.58) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL6929100 | 0.94 | GPR119 (0.52) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL6925447 | 0.92 | GPR119 (0.53) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL6928672 | 0.92 | GPR119 (0.53) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL7388717 | 0.92 | GPR119 (0.53) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL6926256 | 0.92 | GPR119 (0.51) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL6926981 | 0.91 | F10 (0.49) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL6923957 | 0.91 | GPR119 (0.51) | F10PLGPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990646-B1 | PROCESS FOR PREPARING 3-(7-AMIDINO-2-NAPHTHYL)-2-PHENYLPROPIONIC ACID DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2004-04-28 | — | — | EP | disclosed |
| US-6342609-B2 | REACTING A NITRILE COMPOUND OR SALT WITH HYDROXYLAMINE COMPOUND TO FORM AMIDOXIME COMPOUND AS AN INTERMEIDATE, REDUCING THE INTERMEDIATE TO FORM AMIDINE COMPOUND | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-01-29 | — | — | US | disclosed |
| US-20010001802-A1 | PROCESS FOR PREPARING 3-(7-AMIDINO-2-NAPHTHYL)-2-PHENYLPROPIONIC ACID DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-05-24 | — | — | US | disclosed |
| EP-0990646-A1 | PROCESS FOR PREPARING 3-(7-AMIDINO-2-NAPHTHYL)-2-PHENYLPROPIONIC ACID DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010001802-A1 | PROCESS FOR PREPARING 3-(7-AMIDINO-2-NAPHTHYL)-2-PHENYLPROPIONIC ACID DERIVATIVES | PROC, APEH, F7 | F10 41/4885PLG 31/4885PRSS1 879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.