Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.59 |
| ▸ | PLG | P00747 | 3/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.59 |
| ▸ | PLAT | P00750 | 1/20 | 0.59 |
| ▸ | F2 | P00734 | 2/20 | 0.56 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.52 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7387778 | 1.00 | F10 (0.59) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL6815738 | 1.00 | F10 (0.59) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL7383597 | 0.95 | GPR119 (0.58) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL6929100 | 0.94 | GPR119 (0.52) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL6925447 | 0.92 | GPR119 (0.53) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL6928672 | 0.92 | GPR119 (0.53) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL7388717 | 0.92 | GPR119 (0.53) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL6926256 | 0.92 | GPR119 (0.51) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL6926981 | 0.91 | F10 (0.49) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL6923957 | 0.91 | GPR119 (0.51) | F10PLGPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620991-A | ANTICOAGULANTS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| US-5576343-A | ANTICOAGULANTS; BLOOD-COAGULATION FACTOR X INHIBITORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0540051-B1 | Aromatic amidine derivatives and salts thereof | DAIICHI SEIYAKU CO (JP) | 1996-04-03 | — | — | EP | disclosed |
| EP-0540051-A1 | Aromatic amidine derivatives and salts thereof | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-05-05 | — | — | EP | disclosed |