Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815439 | 0.89 | CA2 (0.55) | CA2KMT2AMEN1LMNACTSS | |
| SCHEMBL8381584 | 0.88 | CA2 (0.64) | CA2KMT2AMEN1LMNACTSS | |
| SCHEMBL6814877 | 0.87 | CA2 (0.49) | CA2KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL6819858 | 0.87 | CA2 (0.49) | CA2KMT2AMEN1LMNACTSS | |
| SCHEMBL6554729 | 0.87 | CA2 (0.49) | CA2KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL7619034 | 0.84 | CA2 (0.55) | CA2KMT2AMEN1CA1SMN1; SMN2 | |
| SCHEMBL6813383 | 0.82 | CA2 (0.65) | CA2KMT2AMEN1CTSSCTSK | |
| SCHEMBL6555031 | 0.82 | CA2 (0.65) | CA2KMT2AMEN1CTSSCTSK | |
| SCHEMBL6554814 | 0.78 | CA2 (0.49) | CA2KMT2AMEN1LMNAMAPT | |
| SCHEMBL6816083 | 0.78 | KMT2A (0.48) | CA2KMT2AMEN1LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140799-B1 | NOVEL PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-01-02 | — | — | EP | claimed |
| US-6469005-B1 | CONTROLLING AND PROTECTING AGAINST PHYTOPATHOGENIC MICROORGANISMS | SYNGENTA PARTICIPATIONS AG (CH) | 2002-10-22 | — | — | US | claimed |
| EP-1140799-B1 | NOVEL PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-01-02 | — | — | EP | disclosed |
| US-6469005-B1 | CONTROLLING AND PROTECTING AGAINST PHYTOPATHOGENIC MICROORGANISMS | SYNGENTA PARTICIPATIONS AG (CH) | 2002-10-22 | — | — | US | disclosed |