Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554729 | 1.00 | CA2 (0.49) | CA2KMT2ALMNAPOLBGAA | |
| SCHEMBL6819858 | 0.92 | CA2 (0.49) | CA2KMT2ALMNAMEN1 | |
| SCHEMBL7610664 | 0.87 | KMT2A (0.43) | KMT2ALMNAPOLBGAAALDH1A1 | |
| SCHEMBL6815934 | 0.87 | CA2 (0.54) | CA2KMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL6815439 | 0.85 | CA2 (0.55) | CA2KMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL82268 | 0.85 | KMT2A (0.48) | KMT2ALMNAPOLBGAAALDH1A1 | |
| SCHEMBL483297 | 0.85 | KMT2A (0.48) | KMT2ALMNAPOLBGAAALDH1A1 | |
| SCHEMBL22264508 | 0.85 | CNR1 (0.47) | KMT2ALMNAPOLBGAAALDH1A1 | |
| SCHEMBL29419083 | 0.85 | KMT2A (0.48) | KMT2ALMNAPOLBGAAALDH1A1 | |
| SCHEMBL157178 | 0.85 | KMT2A (0.48) | KMT2ALMNAPOLBGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140799-B1 | NOVEL PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-01-02 | — | — | EP | claimed |
| US-6469005-B1 | CONTROLLING AND PROTECTING AGAINST PHYTOPATHOGENIC MICROORGANISMS | SYNGENTA PARTICIPATIONS AG (CH) | 2002-10-22 | — | — | US | claimed |
| EP-1140799-A1 | NOVEL PROPARGYLETHER DERIVATIVES | Syngenta Participations AG (CH) | 2001-10-10 | — | — | EP | claimed |
| WO-2000041998-A1 | NOVEL PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-07-20 | — | — | WO | claimed |
| EP-1140799-B1 | NOVEL PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-01-02 | — | — | EP | disclosed |
| US-6469005-B1 | CONTROLLING AND PROTECTING AGAINST PHYTOPATHOGENIC MICROORGANISMS | SYNGENTA PARTICIPATIONS AG (CH) | 2002-10-22 | — | — | US | disclosed |
| EP-1140799-A1 | NOVEL PROPARGYLETHER DERIVATIVES | Syngenta Participations AG (CH) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000041998-A1 | NOVEL PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-07-20 | — | — | WO | disclosed |