Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | TK2 | O00142 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819502 | 0.89 | LMNA (0.39) | LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL8165992 | 0.85 | LMNA (0.55) | LMNASMN1; SMN2ALOX12ADRA1ATK2 | |
| SCHEMBL9372470 | 0.84 | LMNA (0.35) | LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL9372482 | 0.84 | LMNA (0.35) | LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL6815457 | 0.84 | DNMT1 (0.34) | — | |
| SCHEMBL6820230 | 0.83 | DNMT1 (0.34) | — | |
| SCHEMBL9368222 | 0.82 | LMNA (0.36) | LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL9368232 | 0.82 | LMNA (0.36) | LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL6819039 | 0.81 | DNMT1 (0.33) | — | |
| SCHEMBL18866641 | 0.80 | TYMP (0.35) | LMNASMN1; SMN2ALOX12ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0978569-B1 | METHOD OF DNA SEQUENCING | RIKAGAKU KENKYUSHO (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-6365350-B1 | REACTING RIBONUCLEOTIDE 5'-TRIPHOSPHATES AND 3'-DEOXY NUCLEOTIDE TRIPHOSPHATES WITH RNA POLYMERASE AND DNA FRAGMENT CONTAINING A PROMOTER SEQUENCE FOR THE POLYMERASE, THEN SEPARATING THE TRANSCRIPTION PRODUCT AND SEQUENCING IT | THE INSTITUTE OF PHYSICAL AND CHEMICAL RESEARCH (JP) | 2002-04-02 | — | — | US | disclosed |
| US-6265569-B1 | HAS ALKYL LINKER INCLUDING DOUBLE OR TRIPLE BOND WHICH ATTACHES FLUORESCENT MOLECULE TO NUCLEOTIDE; FOR TERMINATORS IN DNA SEQUENCING USING RNA POLYMERASES | THE INSTITUTE OF PHYSICAL AND CHEMICAL RESEARCH (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1046648-A1 | 3'-DEOXYRIBONUCLEOTIDE DERIVATIVES | THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH (JP) | 2000-10-25 | — | — | EP | disclosed |
| EP-0978569-A1 | METHOD OF DNA SEQUENCING | THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH (JP) | 2000-02-09 | — | — | EP | disclosed |