Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368222 | 1.00 | LMNA (0.36) | LMNASMN1; SMN2ALOX12ADRA1AALDH1A1 | |
| SCHEMBL9372482 | 0.97 | LMNA (0.35) | LMNASMN1; SMN2ALOX12ADRA1AALDH1A1 | |
| SCHEMBL9372470 | 0.97 | LMNA (0.35) | LMNASMN1; SMN2ALOX12ADRA1AALDH1A1 | |
| SCHEMBL2284109 | 0.95 | LMNA (0.37) | LMNASMN1; SMN2ALOX12ADRA1AALDH1A1 | |
| SCHEMBL8476367 | 0.89 | LMNA (0.38) | LMNASMN1; SMN2ALOX12ADRA1AALDH1A1 | |
| SCHEMBL8476369 | 0.89 | LMNA (0.38) | LMNASMN1; SMN2ALOX12ADRA1AALDH1A1 | |
| SCHEMBL24922883 | 0.87 | LMNA (0.34) | LMNASMN1; SMN2ALOX12ADRA1AALDH1A1 | |
| SCHEMBL9370017 | 0.82 | TK1 (0.41) | LMNASMN1; SMN2ALDH1A1ALBMAPK1 | |
| SCHEMBL9369069 | 0.82 | TK1 (0.41) | LMNASMN1; SMN2ALDH1A1ALBMAPK1 | |
| SCHEMBL6815935 | 0.82 | LMNA (0.36) | LMNASMN1; SMN2ALOX12ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251786-B1 | Alkynylamino-nucleotides | DU PONT (US) | 1994-11-30 | — | — | EP | disclosed |
| US-5151507-A | Alkynylamino-nucleotides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-29 | — | — | US | disclosed |
| US-5047519-A | Alkynylamino-nucleotides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-09-10 | — | — | US | disclosed |