Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5824190 | 0.90 | L3MBTL1 (0.57) | L3MBTL1APPKMT2AALDH1A1KDM4E | |
| SCHEMBL14107981 | 0.88 | L3MBTL1 (0.59) | L3MBTL1APPKMT2AALDH1A1KDM4E | |
| SCHEMBL4668387 | 0.88 | L3MBTL1 (0.55) | L3MBTL1APPKMT2AALDH1A1KDM4E | |
| SCHEMBL4863815 | 0.83 | L3MBTL1 (0.53) | L3MBTL1APPKMT2AALDH1A1KDM4E | |
| SCHEMBL9310449 | 0.83 | L3MBTL1 (0.59) | L3MBTL1OPRD1OPRK1APPKMT2A | |
| SCHEMBL9528495 | 0.82 | APP (0.66) | L3MBTL1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL4866314 | 0.81 | L3MBTL1 (0.51) | L3MBTL1APPKMT2AALDH1A1KDM4E | |
| SCHEMBL9312413 | 0.80 | L3MBTL1 (0.65) | L3MBTL1APPALDH1A1KDM4EGAA | |
| SCHEMBL4981287 | 0.80 | L3MBTL1 (0.57) | L3MBTL1OPRD1OPRK1APPKMT2A | |
| SCHEMBL7570603 | 0.79 | L3MBTL1 (0.56) | L3MBTL1OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026855-A1 | METHOD FOR MANUFACTURE OF DIHYDROISOBENZOFURAN DERIVATIVES | H. LUNDBECK A/S (DK) | 2004-04-01 | — | — | WO | disclosed |