Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.43 |
| ▸ | PPARG | P37231 | 13/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817082 | 0.82 | PPARA (0.44) | PPARAPPARGPPARD | |
| SCHEMBL6919905 | 0.77 | PPARD (0.59) | PPARAPPARGPPARD | |
| SCHEMBL6816310 | 0.77 | PPARA (0.43) | PPARAPPARGPPARDCYP11B1CYP11B2 | |
| SCHEMBL3961926 | 0.74 | HTR2A (0.52) | PPARAPPARD | |
| SCHEMBL6816298 | 0.73 | PPARA (0.37) | PPARAPPARGPPARDCYP11B1CYP11B2 | |
| SCHEMBL3970689 | 0.73 | HSD17B1 (0.37) | PPARAPPARGPPARDCYP11B1CYP11B2 | |
| SCHEMBL3964872 | 0.68 | THRA (0.38) | PPARAPPARD | |
| SCHEMBL3965573 | 0.67 | POLB (0.41) | PPARDCYP11B1CYP11B2 | |
| SCHEMBL19984873 | 0.66 | CYP11B1 (0.55) | PPARAPPARDCYP11B1CYP11B2 | |
| SCHEMBL3964420 | 0.66 | HSD17B1 (0.44) | PPARAPPARDCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004011446-A1 | INDANE, DIHYDROBENZOFURAN, AND TETRAHYDRONAPHTHALENE CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIDIABETICS | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-02-05 | — | — | WO | disclosed |