Kinetin

Kinetin

SCHEMBL6816355

OC[C@H]1OC(O)[C@H](O)[C@@H]1O.c1coc(CNc2ncnc3nc[nH]c23)c1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 7/20 0.72
TP53 P04637 4/20 0.72
TSHR P16473 3/20 0.72
CYP1A2 P05177 3/20 0.72
ADORA3 P0DMS8 2/20 0.72
KDR P35968 2/20 0.72
ALOX15 P16050 2/20 0.72
HIF1A Q16665 2/20 0.72
MEN1 O00255 1/20 0.72
KMT2A Q03164 1/20 0.72
LMNA P02545 4/20 0.54
PAX8 Q06710 2/20 0.54
SLC29A1 Q99808 1/20 0.54
MITF O75030 1/20 0.54
CDK2 P24941 2/20 0.47
MAPK1 P28482 2/20 0.47
CYP2D6 P10635 1/20 0.47
AURKA O14965 1/20 0.45
DAPK3 O43293 1/20 0.45
JAK2 O60674 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Kinetin SCHEMBL29453466 0.85 SMN1; SMN2 (1.00) SMN1; SMN2TP53TSHRCYP1A2ADORA3
Kinetin SCHEMBL15706 0.85 SMN1; SMN2 (1.00) SMN1; SMN2TP53TSHRCYP1A2ADORA3
6-Benzylaminopurine SCHEMBL15067419 0.85 LMNA (0.69) SMN1; SMN2TP53TSHRCYP1A2ADORA3
Kinetin SCHEMBL584401 0.84 SMN1; SMN2 (0.97) SMN1; SMN2TP53TSHRCYP1A2ADORA3
Kinetin SCHEMBL15941491 0.81 SMN1; SMN2 (0.86) SMN1; SMN2TP53TSHRCYP1A2ADORA3
Kinetin SCHEMBL25270416 0.80 SMN1; SMN2 (0.84) SMN1; SMN2TP53TSHRCYP1A2ADORA3
Kinetin SCHEMBL30320041 0.80 SMN1; SMN2 (0.84) SMN1; SMN2TP53TSHRCYP1A2ADORA3
Ribose (Furanose) SCHEMBL5519867 0.78 CYP1A2 (0.72) SMN1; SMN2TP53TSHRCYP1A2ADORA3
Ribose (Furanose) SCHEMBL18789082 0.75 TSHR (0.58) SMN1; SMN2TP53TSHRCYP1A2ADORA3
Kinetin SCHEMBL28188657 0.75 SMN1; SMN2 (0.70) SMN1; SMN2TP53TSHRCYP1A2ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3229771-B1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIV PALACKEHO (CZ) 2024-04-03 EP disclosed
EP-3229772-B1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIV PALACKEHO (CZ) 2020-04-29 EP disclosed
US-10550144-B2 6-aryl-9-glycosylpurines and use thereof UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2020-02-04 US disclosed
US-10100077-B2 6-aryl-9-glycosylpurines and use thereof UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2018-10-16 US disclosed
US-20170334943-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2017-11-23 US disclosed
US-20170326168-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2017-11-16 US disclosed
EP-3229772-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF Univerzita Palackého v Olomouci (CZ) 2017-10-18 EP disclosed
EP-3229771-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF Univerzita Palackého v Olomouci (CZ) 2017-10-18 EP disclosed
WO-2016091236-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2016-06-16 WO disclosed
WO-2016091235-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2016-06-16 WO disclosed
EP-0475160-B2 Preparation for drug application in minute droplet form IDEA AG (DE) 2004-07-14 EP disclosed
EP-0475160-B1 Preparation for drug application in minute droplet form IDEA AG (DE) 1996-02-14 EP disclosed
EP-0475160-A1 Preparation for drug application in minute droplet form Cevc, Gregor, Prof. Dr. (DE) 1992-03-18 EP disclosed
WO-1992003122-A1 PREPARATION FOR APPLICATION OF ACTIVE SUBSTANCES IN THE FORM OF MINIMUM-SIZED DROPLETS CEVC GREGOR (DE) 1992-03-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170326168-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF GART, DAO, GLA SMN1; SMN2 3612/4885TP53 3135/4885TSHR 2378/4885
US-10550144-B2 6-aryl-9-glycosylpurines and use thereof GART, DAO, GLA SMN1; SMN2 3612/4885TP53 3135/4885TSHR 2378/4885
US-20170334943-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNG, FUT6, GART SMN1; SMN2 2553/4885TP53 2090/4885TSHR 2559/4885
US-10100077-B2 6-aryl-9-glycosylpurines and use thereof UNG, FUT6, GART SMN1; SMN2 2553/4885TP53 2090/4885TSHR 2559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.