Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816474 | 0.93 | GAA (0.52) | GAAALDH1A1CNR1CTSDKMT2A | |
| SCHEMBL6816190 | 0.92 | LMNA (0.52) | ALDH1A1KMT2ALMNATHRB | |
| SCHEMBL6812132 | 0.91 | ALDH1A1 (0.44) | GAAALDH1A1CNR1CTSDKMT2A | |
| SCHEMBL6815534 | 0.91 | ALDH1A1 (0.48) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6817053 | 0.89 | PPARD (0.43) | ALDH1A1LMNATP53 | |
| SCHEMBL5889715 | 0.87 | GAA (0.53) | GAAALDH1A1CNR1CTSDKMT2A | |
| SCHEMBL31609211 | 0.87 | GAA (0.53) | GAAALDH1A1CNR1CTSDKMT2A | |
| SCHEMBL31609209 | 0.87 | GAA (0.53) | GAAALDH1A1CNR1CTSDKMT2A | |
| SCHEMBL31609210 | 0.87 | GAA (0.53) | GAAALDH1A1CNR1CTSDKMT2A | |
| SCHEMBL6815430 | 0.87 | MAPT (0.48) | ALDH1A1CTSDKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021183-B1 | A COMBINATION OF A SELECTIVE 5-HT1A ANTAGONIST AND A SELECTIVE h5-HT1B ANTAGONIST OR PARTIAL AGONIST | ASTRAZENECA AB (SE) | 2004-03-17 | — | — | EP | claimed |
| EP-1140799-B1 | NOVEL PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-01-02 | — | — | EP | claimed |
| US-6469005-B1 | CONTROLLING AND PROTECTING AGAINST PHYTOPATHOGENIC MICROORGANISMS | SYNGENTA PARTICIPATIONS AG (CH) | 2002-10-22 | — | — | US | claimed |
| EP-1140799-A1 | NOVEL PROPARGYLETHER DERIVATIVES | Syngenta Participations AG (CH) | 2001-10-10 | — | — | EP | claimed |
| WO-2000041998-A1 | NOVEL PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-07-20 | — | — | WO | claimed |
| EP-1140799-B1 | NOVEL PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-01-02 | — | — | EP | disclosed |
| US-6469005-B1 | CONTROLLING AND PROTECTING AGAINST PHYTOPATHOGENIC MICROORGANISMS | SYNGENTA PARTICIPATIONS AG (CH) | 2002-10-22 | — | — | US | disclosed |
| EP-1140799-A1 | NOVEL PROPARGYLETHER DERIVATIVES | Syngenta Participations AG (CH) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000041998-A1 | NOVEL PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-07-20 | — | — | WO | disclosed |