Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816673 | 0.86 | ALDH1A1 (0.63) | ALDH1A1HTTGAAKDM4EPOLB | |
| SCHEMBL6215242 | 0.83 | ALDH1A1 (0.71) | ALDH1A1HTTKDM4EPOLBHPGD | |
| SCHEMBL26848902 | 0.82 | ALDH1A1 (0.69) | ALDH1A1HTTKDM4EPOLBHPGD | |
| SCHEMBL14447745 | 0.82 | ALDH1A1 (0.69) | ALDH1A1HTTKDM4EPOLBHPGD | |
| SCHEMBL8269525 | 0.82 | ALDH1A1 (0.69) | ALDH1A1HTTKDM4EPOLBHPGD | |
| SCHEMBL4071532 | 0.82 | ALDH1A1 (0.69) | ALDH1A1HTTKDM4EPOLBHPGD | |
| SCHEMBL20827023 | 0.81 | ALDH1A1 (0.75) | ALDH1A1HTTKDM4EPOLBHPGD | |
| SCHEMBL30227993 | 0.81 | ALDH1A1 (0.68) | ALDH1A1HTTKDM4EPOLBHPGD | |
| SCHEMBL29774282 | 0.79 | HTT (0.58) | ALDH1A1HTTGAAKDM4EPOLB | |
| SCHEMBL24340315 | 0.78 | ALDH1A1 (0.64) | ALDH1A1HTTKDM4EPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | disclosed |