Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8269525 | 1.00 | ALDH1A1 (0.69) | ALDH1A1HTTPOLBHPGDSMN1; SMN2 | |
| SCHEMBL14447745 | 1.00 | ALDH1A1 (0.69) | ALDH1A1HTTPOLBHPGDSMN1; SMN2 | |
| SCHEMBL6215242 | 0.89 | ALDH1A1 (0.71) | ALDH1A1HTTPOLBHPGDSMN1; SMN2 | |
| SCHEMBL20267750 | 0.88 | ALDH1A1 (0.55) | ALDH1A1HTTPOLBHPGDSMN1; SMN2 | |
| SCHEMBL4071532 | 0.87 | ALDH1A1 (0.69) | ALDH1A1HTTPOLBHPGDSMN1; SMN2 | |
| SCHEMBL20827023 | 0.86 | ALDH1A1 (0.75) | ALDH1A1HTTPOLBHPGDSMN1; SMN2 | |
| SCHEMBL30227993 | 0.86 | ALDH1A1 (0.68) | ALDH1A1HTTPOLBHPGDSMN1; SMN2 | |
| SCHEMBL24339466 | 0.83 | ALDH1A1 (0.64) | ALDH1A1HTTPOLBHPGDSMN1; SMN2 | |
| SCHEMBL24340334 | 0.83 | MAPT (0.68) | ALDH1A1HTTPOLBHPGDSMN1; SMN2 | |
| SCHEMBL2635405 | 0.83 | ALDH1A1 (0.72) | ALDH1A1HTTPOLBHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12565498-B2 | β-lactamase inhibitors and their preparation | NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES (CN) | 2026-03-03 | — | — | US | disclosed |
| CN-115151544-B | Beta-lactamase inhibitor and preparation thereof | 宁夏农林科学院 | 2024-08-16 | — | — | CN | disclosed |
| US-20230365561-A1 | BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION | NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES (CN) | 2023-11-16 | — | — | US | disclosed |
| US-20230365561-A1 | BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION | NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES (CN) | 2023-11-16 | — | — | US | disclosed |
| US-20230365561-A1 | BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION | NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES (CN) | 2023-11-16 | — | — | US | disclosed |
| EP-4146650-A1 | BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION | Ningxia Academy of Agriculture and Forestry Sciences (CN) | 2023-03-15 | — | — | EP | disclosed |
| CN-115151544-A | Beta-lactamase inhibitors and preparation thereof | 宁夏农林科学院 | 2022-10-04 | — | — | CN | disclosed |
| WO-2022047603-A1 | BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION | NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES (CN) | 2022-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12565498-B2 | β-lactamase inhibitors and their preparation | PGLS, MGAM, OSTC | ALDH1A1 452/4885HTT 4368/4885POLB 978/4885 |
| US-20230365561-A1 | BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION | MGAM, LCT, GANAB | ALDH1A1 315/4885HTT 4822/4885POLB 266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.