Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | HTR1B | P28222 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.52 |
| ▸ | HTR1F | P30939 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820991 | 0.86 | HTR6 (0.52) | HTR6HTR1BHTR7HTR1AHTR1D | |
| SCHEMBL6820240 | 0.86 | HTR6 (0.52) | HTR6HTR1BHTR7HTR1AHTR1D | |
| SCHEMBL3552548 | 0.86 | HTR1B (0.48) | HTR6HTR1BHTR7KMT2AALDH1A1 | |
| SCHEMBL6817332 | 0.85 | HTR6 (0.70) | HTR6HTR1BHTR7HTR1AHTR1D | |
| SCHEMBL6922481 | 0.83 | HTR7 (0.49) | HTR6HTR1BHTR7KMT2AALDH1A1 | |
| SCHEMBL24877919 | 0.78 | HTR6 (0.76) | HTR6HTR1BHTR7HTR1AHTR1D | |
| SCHEMBL28466414 | 0.78 | KMT2A (0.54) | HTR6HTR1BHTR7HTR1AHTR1D | |
| SCHEMBL30485872 | 0.78 | HTR6 (0.76) | HTR6HTR1BHTR7HTR1AHTR1D | |
| SCHEMBL6820963 | 0.77 | KDM4E (0.46) | HTR6HTR1BHTR7HTR1AHTR1D | |
| SCHEMBL6817370 | 0.74 | P2RX4 (0.46) | KMT2AALDH1A1MEN1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |