Adamantane

Adamantane

SCHEMBL6817495

C1C2CC3CC1CC(C2)C3.O=C(O)C=CO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.48
CYP2C9 P11712 1/20 0.48
TSHR P16473 3/20 0.44
TP53 P04637 1/20 0.42
EGLN1 Q9GZT9 1/20 0.42
EGLN3 Q9H6Z9 1/20 0.42
HSD11B1 P28845 1/20 0.36
POLB P06746 1/20 0.34
ATM Q13315 1/20 0.34
ESR1 P03372 1/20 0.34
HTT P42858 1/20 0.31
NPC1 O15118 1/20 0.31
GAA P10253 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adamantane SCHEMBL2307499 0.85 THRB (0.61) THRBCYP2C9TSHRTP53EGLN1
Adamantane SCHEMBL2307508 0.85 THRB (0.61) THRBCYP2C9TSHRTP53EGLN1
SCHEMBL110441 0.82
SCHEMBL3367907 0.82
SCHEMBL10601607 0.82
SCHEMBL28175029 0.79 THRB (0.36) THRBCYP2C9TSHRTP53EGLN1
SCHEMBL27960022 0.78
SCHEMBL28053415 0.78
Ammonia Solution, Strong SCHEMBL9959012 0.78
Ethylene SCHEMBL9567548 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1041442-B1 Chemical amplification type positive resist SUMITOMO CHEMICAL CO (JP) 2004-10-27 EP disclosed
US-6348297-B1 COMPOSITION COMPRISING ACID GENERATOR COMPRISING ALIPHATIC SULFONIUM SALT, TRIPHENYLSULFONIUM OR DIPHENYLIODONIUM SALT,RESIN HAVING ACID-LABILE GROUP WHICH IS INSOLUBLE IN ALKALI BUT BECOMES SOLUBLE BY ACTION OF ACID SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-02-19 US disclosed
EP-1041442-A1 Chemical amplification type positive resist SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-04 EP disclosed