Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23809728 | 0.87 | BACE1 (0.52) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL12799797 | 0.86 | HTT (0.44) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL14700584 | 0.86 | BACE1 (0.45) | HPGDCYP3A4BACE1KMT2APOLB | |
| SCHEMBL12445354 | 0.82 | HTT (0.46) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL14700551 | 0.82 | KMT2A (0.46) | KDM4EHSD17B10TP53GAAMAPT | |
| SCHEMBL3156904 | 0.80 | KDM4E (0.52) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL3326825 | 0.79 | TUBB4A (0.63) | GAAMAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL14700496 | 0.79 | POLB (0.51) | GAATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14700588 | 0.79 | TUBB4A (0.50) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL3600800 | 0.78 | HSD17B10 (0.55) | HTTKDM4EHSD17B10TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004009574-A1 | SYNTHESIS OF DISCODERMOLIDE | NOVARTIS AG (CH) | 2004-01-29 | — | — | WO | disclosed |