Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6082133 | 1.00 | CRHR1 (0.39) | CRHR1SOS1IDO1NR1I2 | |
| SCHEMBL6822466 | 0.89 | IDO1 (0.35) | CRHR1SOS1IDO1NR1I2 | |
| SCHEMBL6082902 | 0.89 | IDO1 (0.35) | CRHR1SOS1IDO1NR1I2 | |
| SCHEMBL6082536 | 0.89 | IDO1 (0.35) | IDO1 | |
| SCHEMBL6081890 | 0.85 | SOS1 (0.39) | CRHR1SOS1IDO1NR1I2 | |
| SCHEMBL6082049 | 0.84 | SOS1 (0.38) | CRHR1SOS1IDO1 | |
| SCHEMBL6082059 | 0.84 | SOS1 (0.38) | CRHR1SOS1IDO1 | |
| SCHEMBL6084266 | 0.83 | IDO1 (0.35) | SOS1IDO1 | |
| SCHEMBL6082037 | 0.83 | CRHR1 (0.40) | CRHR1IDO1NR1I2 | |
| SCHEMBL6083293 | 0.82 | CRHR1 (0.44) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004031189-A1 | PYRIDINO AND PYRIMIDINO PYRAZINONES FOR TREATMENT OF ANXIETY AND DEPRESSION | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2004-04-15 | — | — | WO | disclosed |