Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818611 | 0.91 | KDM4E (0.37) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL6817659 | 0.90 | DHODH (0.35) | KDM4EALDH1A1KMT2AALBHIF1A | |
| SCHEMBL6817836 | 0.90 | ALB (0.38) | KDM4EKMT2AMEN1HTTALB | |
| SCHEMBL6821646 | 0.89 | KDM4E (0.38) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL6821640 | 0.87 | MAPK14 (0.36) | ALDH1A1ALBHIF1ALRRK2TRPM4 | |
| SCHEMBL6818871 | 0.86 | DHODH (0.42) | KDM4EALBLRRK2SMN1; SMN2DHODH | |
| SCHEMBL6818178 | 0.85 | HIF1A (0.43) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL6819582 | 0.85 | STING1 (0.39) | KDM4EALBLRRK2SMN1; SMN2DHODH | |
| SCHEMBL6817656 | 0.85 | MAPK14 (0.36) | ALDH1A1ALBHIF1ALRRK2TRPM4 | |
| SCHEMBL6817683 | 0.83 | HIF1A (0.44) | KDM4EALDH1A1KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |