Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAK | O14976 | 1/20 | 0.34 |
| ▸ | STK16 | O75716 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818843 | 0.91 | PPARG (0.42) | PPARGKDM4EGSK3AGSK3BLRRK2 | |
| SCHEMBL6819582 | 0.90 | STING1 (0.39) | DHODHPPARGKDM4EGSK3AGSK3B | |
| SCHEMBL6817659 | 0.87 | DHODH (0.35) | DHODHKDM4EALBSMN1; SMN2 | |
| SCHEMBL6818019 | 0.86 | KDM4E (0.38) | DHODHKDM4EGSK3AGSK3BLRRK2 | |
| SCHEMBL6821640 | 0.86 | MAPK14 (0.36) | DHODHGSK3AGSK3BLRRK2ALB | |
| SCHEMBL6817796 | 0.84 | PPARG (0.37) | PPARGGSK3AGSK3BLRRK2CYP11B1 | |
| SCHEMBL6818178 | 0.84 | HIF1A (0.43) | KDM4ENPC1RAB9ALRRK2ALB | |
| SCHEMBL6821784 | 0.83 | HIF1A (0.38) | DHODHKDM4EGSK3AGSK3BALB | |
| SCHEMBL6818640 | 0.83 | PPARG (0.39) | PPARGGSK3AGSK3BLRRK2CYP11B1 | |
| SCHEMBL6817656 | 0.83 | MAPK14 (0.36) | DHODHGSK3AGSK3BLRRK2ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |