Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817683 | 0.98 | HIF1A (0.44) | HIF1AKDM4EGAAMAPTMAPK1 | |
| SCHEMBL6821640 | 0.90 | MAPK14 (0.36) | HIF1AMAPTSMN1; SMN2ALDH1A1TRPM4 | |
| SCHEMBL6822192 | 0.89 | AGPAT2 (0.35) | HIF1AKDM4EGAAMAPTMAPK1 | |
| SCHEMBL6822443 | 0.89 | HIF1A (0.46) | HIF1AKDM4EGAAMAPTALDH1A1 | |
| SCHEMBL6818399 | 0.87 | HIF1A (0.46) | HIF1AKDM4EMAPTALDH1A1HSD17B10 | |
| SCHEMBL6817656 | 0.87 | MAPK14 (0.36) | HIF1AMAPTSMN1; SMN2ALDH1A1TRPM4 | |
| SCHEMBL6822476 | 0.85 | HIF1A (0.44) | HIF1AKDM4EGAAMAPTALDH1A1 | |
| SCHEMBL6818019 | 0.85 | KDM4E (0.38) | HIF1AKDM4ESMN1; SMN2ALDH1A1TRPM4 | |
| SCHEMBL6819458 | 0.85 | CETP (0.35) | SMN1; SMN2ALDH1A1TRPM4TSHRTP53 | |
| SCHEMBL6821670 | 0.84 | HIF1A (0.41) | HIF1AKDM4EGAAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |