Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.53 |
| ▸ | ITGAV | P06756 | 2/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 5/20 | 0.48 |
| ▸ | MMP9 | P14780 | 5/20 | 0.48 |
| ▸ | MMP8 | P22894 | 3/20 | 0.48 |
| ▸ | MMP12 | P39900 | 3/20 | 0.48 |
| ▸ | MMP14 | P50281 | 3/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CTRC | Q99895 | 1/20 | 0.46 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL600046 | 0.94 | ALDH1A1 (0.52) | ITGB3ITGAVITGA2BALDH1A1MEN1 | |
| SCHEMBL15308918 | 0.89 | ALDH1A1 (0.50) | ITGB3ITGAVITGA2BALDH1A1MEN1 | |
| SCHEMBL4058881 | 0.89 | SLC1A3 (0.55) | ITGB3ITGAVITGA2BALDH1A1MEN1 | |
| SCHEMBL18696985 | 0.86 | ITGB3 (0.57) | ITGB3ITGAVITGA2BALDH1A1MEN1 | |
| SCHEMBL30309011 | 0.85 | ITGB3 (0.65) | ITGB3ITGAVITGA2BALDH1A1MEN1 | |
| SCHEMBL12044849 | 0.85 | SLC1A3 (0.54) | ITGB3ITGAVITGA2BALDH1A1MEN1 | |
| SCHEMBL6818664 | 0.84 | HDAC3 (0.45) | ITGB3ITGAVITGA2BALDH1A1MEN1 | |
| SCHEMBL7357439 | 0.83 | SLC1A3 (0.52) | ITGB3ITGAVITGA2BALDH1A1MEN1 | |
| SCHEMBL23039617 | 0.83 | HDAC2 (0.52) | ITGB3ITGAVITGA2BSLC1A3SLC1A2 | |
| SCHEMBL3898276 | 0.83 | SLC1A3 (0.57) | ITGB3ITGAVITGA2BALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004020402-A1 | SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-03-11 | — | — | WO | claimed |
| WO-2004020402-A1 | SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-03-11 | — | — | WO | disclosed |