Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 8/20 | 0.39 |
| ▸ | ALB | P02768 | 2/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818761 | 0.92 | ALB (0.39) | ALBLRRK2PDE10AGSK3AGSK3B | |
| SCHEMBL6819285 | 0.90 | ALB (0.40) | ALBGSK3AGSK3BBRD4POLB | |
| SCHEMBL6818975 | 0.90 | PPARG (0.38) | STING1ALBLRRK2PDE10AGSK3A | |
| SCHEMBL6818408 | 0.85 | STING1 (0.41) | STING1ALBLRRK2PDE10AGSK3A | |
| SCHEMBL6821747 | 0.85 | BRD4 (0.39) | ALBLRRK2PDE10AGSK3AGSK3B | |
| SCHEMBL6814844 | 0.85 | STING1 (0.40) | STING1ALBLRRK2PDE10AGSK3A | |
| SCHEMBL6822734 | 0.84 | STING1 (0.44) | STING1ALBLRRK2TP53POLB | |
| SCHEMBL6818405 | 0.83 | ALB (0.37) | ALBPDE10ABRD4 | |
| SCHEMBL6817479 | 0.83 | ALB (0.37) | ALBLRRK2PDE10AGSK3AGSK3B | |
| SCHEMBL6821951 | 0.83 | HIF1A (0.43) | ALBLRRK2TP53POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |