Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 2/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | GAK | O14976 | 1/20 | 0.36 |
| ▸ | STK16 | O75716 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | NEK2 | P51955 | 1/20 | 0.36 |
| ▸ | STK3 | Q13188 | 1/20 | 0.36 |
| ▸ | STK11 | Q15831 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819285 | 0.93 | ALB (0.40) | GSK3AGSK3BALBBRD4 | |
| SCHEMBL6817796 | 0.92 | PPARG (0.37) | PPARGCYP11B1CYP11B2GSK3AGSK3B | |
| SCHEMBL6818761 | 0.91 | ALB (0.39) | PPARGGSK3AGSK3BALBLRRK2 | |
| SCHEMBL6817333 | 0.91 | PPARG (0.39) | PPARGCYP11B1CYP11B2GSK3AGSK3B | |
| SCHEMBL6818174 | 0.90 | STING1 (0.39) | GSK3AGSK3BALBLRRK2BRD4 | |
| SCHEMBL6818640 | 0.88 | PPARG (0.39) | PPARGCYP11B1CYP11B2GSK3AGSK3B | |
| SCHEMBL6821747 | 0.86 | BRD4 (0.39) | GSK3AGSK3BALBLRRK2BRD4 | |
| SCHEMBL6818843 | 0.85 | PPARG (0.42) | PPARGCYP11B1CYP11B2GSK3AGSK3B | |
| SCHEMBL6818405 | 0.84 | ALB (0.37) | ALBBRD4PDE10A | |
| SCHEMBL6819061 | 0.84 | ALB (0.38) | GSK3AGSK3BALBBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |