Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822331 | 0.91 | BRD4 (0.39) | BRD4ALBTBXA2RGSK3AGSK3B | |
| SCHEMBL6822221 | 0.91 | ALB (0.39) | BRD4ALBTBXA2RGSK3AGSK3B | |
| SCHEMBL6819285 | 0.91 | ALB (0.40) | BRD4ALBGSK3AGSK3BHIF1A | |
| SCHEMBL6818405 | 0.91 | ALB (0.37) | BRD4ALBTBXA2RHIF1AMCL1 | |
| SCHEMBL6821951 | 0.90 | HIF1A (0.43) | ALBLRRK2HIF1AMAPTMEN1 | |
| SCHEMBL6818761 | 0.86 | ALB (0.39) | BRD4ALBGSK3AGSK3BLRRK2 | |
| SCHEMBL6818975 | 0.86 | PPARG (0.38) | BRD4ALBGSK3AGSK3BLRRK2 | |
| SCHEMBL6818998 | 0.85 | HIF1A (0.39) | ALBGSK3AGSK3BLRRK2HIF1A | |
| SCHEMBL6818765 | 0.85 | ALB (0.37) | BRD4ALBGSK3AGSK3BLRRK2 | |
| SCHEMBL6818174 | 0.85 | STING1 (0.39) | BRD4ALBGSK3AGSK3BLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |