Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CD69 | Q07108 | 1/20 | 0.33 |
| ▸ | CXCR5 | P32302 | 7/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614604 | 0.87 | KMT2A (0.36) | LMNAALDH1A1TSHRBLMKMT2A | |
| SCHEMBL6818043 | 0.85 | ALDH1A1 (0.39) | LMNAUSP2ALDH1A1CYP1A2TSHR | |
| SCHEMBL6818099 | 0.85 | ALDH1A1 (0.46) | LMNAUSP2ALDH1A1CYP1A2TSHR | |
| SCHEMBL14459076 | 0.84 | ALDH1A1 (0.40) | LMNAUSP2ALDH1A1CYP1A2TSHR | |
| SCHEMBL6813335 | 0.84 | HTR1A (0.48) | LMNAUSP2ALDH1A1CYP1A2TSHR | |
| SCHEMBL6818094 | 0.84 | USP2 (0.40) | LMNAUSP2ALDH1A1CYP1A2TSHR | |
| SCHEMBL6817221 | 0.83 | ALDH1A1 (0.39) | LMNAUSP2ALDH1A1CYP1A2TSHR | |
| SCHEMBL6817613 | 0.83 | USP2 (0.39) | LMNAUSP2ALDH1A1CYP1A2TSHR | |
| SCHEMBL6813555 | 0.83 | USP2 (0.39) | LMNAUSP2ALDH1A1CYP1A2TSHR | |
| SCHEMBL6813724 | 0.83 | AKR1B1 (0.44) | LMNAUSP2ALDH1A1CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1180094-B1 | FUSED POLYCYCLIC AMINO ACIDS AS PHARMACEUTICAL AGENTS | WARNER LAMBERT CO (US) | 2004-07-28 | — | — | EP | claimed |
| WO-2007090661-A2 | ACTIVE SUBSTANCE COMBINATION COMPRISING AZOLYLCARBINOL COMPOUNDS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-08-16 | — | — | WO | disclosed |
| EP-1180094-B1 | FUSED POLYCYCLIC AMINO ACIDS AS PHARMACEUTICAL AGENTS | WARNER LAMBERT CO (US) | 2004-07-28 | — | — | EP | disclosed |