Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817481 | 0.98 | S1PR1 (0.36) | S1PR1POLBMAPTTP53ADRB2 | |
| SCHEMBL6833954 | 0.91 | RORC (0.35) | S1PR1POLBMAPTTP53ALB | |
| SCHEMBL6818600 | 0.91 | TP53 (0.34) | S1PR1POLBMAPTTP53ADRB2 | |
| SCHEMBL6822026 | 0.90 | EGLN2 (0.35) | S1PR1POLBMAPTTP53ALB | |
| SCHEMBL6919972 | 0.90 | RXFP1 (0.33) | S1PR1POLBMAPTTP53ALB | |
| SCHEMBL6818246 | 0.90 | TP53 (0.34) | S1PR1POLBMAPTTP53ADRB2 | |
| SCHEMBL6818889 | 0.90 | EGLN2 (0.34) | S1PR1POLBMAPTTP53ALB | |
| SCHEMBL6818406 | 0.89 | RORC (0.34) | S1PR1POLBMAPTTP53ALB | |
| SCHEMBL6819217 | 0.89 | PDE10A (0.37) | S1PR1POLBMAPTTP53ALB | |
| SCHEMBL6819802 | 0.89 | TP53 (0.33) | S1PR1POLBMAPTTP53ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |