Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | GPR183 | P32249 | 1/20 | 0.30 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818625 | 0.94 | MAP2K1 (0.34) | TP53POLBMAPTMAP2K1ALB | |
| SCHEMBL6822336 | 0.92 | MAP2K1 (0.33) | TP53POLBMAPTMAP2K1ALB | |
| SCHEMBL6818167 | 0.91 | RORC (0.34) | MAP2K1ALBRORCS1PR1S1PR3 | |
| SCHEMBL6821300 | 0.90 | ALB (0.33) | TP53POLBMAPTALB | |
| SCHEMBL6818364 | 0.90 | RORC (0.34) | MAP2K1ALBRORCS1PR1S1PR3 | |
| SCHEMBL6818617 | 0.89 | AR (0.33) | TP53POLBMAPTALBRORC | |
| SCHEMBL6819369 | 0.89 | ALB (0.33) | TP53POLBMAPTALB | |
| SCHEMBL6818304 | 0.89 | S1PR1 (0.37) | TP53POLBMAPTALBRORC | |
| SCHEMBL6833954 | 0.88 | RORC (0.35) | TP53POLBMAPTMAP2K1ALB | |
| SCHEMBL6818790 | 0.88 | ALB (0.32) | TP53ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |