Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 4/20 | 0.59 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3313524 | 0.89 | CA2 (0.61) | ALDH1A1HPGDHSD17B10CA2CAMK2A | |
| SCHEMBL23501410 | 0.85 | ALDH1A1 (0.61) | CYP4F2CYP4A11ALDH1A1HPGDHSD17B10 | |
| SCHEMBL6817399 | 0.85 | CA2 (0.58) | CYP4F2CYP4A11ALDH1A1CA2PPARA | |
| SCHEMBL29280882 | 0.78 | FFAR1 (0.65) | CA2FFAR1LMNA | |
| Phenylacetic Acid SCHEMBL29278083 | 0.77 | AKR1B1 (0.74) | CYP4F2CYP4A11ALDH1A1HPGDHSD17B10 | |
| SCHEMBL13191515 | 0.75 | HTT (0.47) | CYP4F2CYP4A11ALDH1A1CA2CAMK2A | |
| SCHEMBL25984402 | 0.75 | CA2 (0.47) | CYP4F2CYP4A11ALDH1A1CA2PPARA | |
| SCHEMBL2996429 | 0.74 | CA2 (0.68) | ALDH1A1HPGDHSD17B10CA2CAMK2A | |
| SCHEMBL9332759 | 0.74 | CYP4A11 (1.00) | CYP4F2CYP4A11ALDH1A1PPARAGAA | |
| SCHEMBL14238643 | 0.74 | CA2 (0.57) | ALDH1A1HPGDHSD17B10CA2CAMK2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237857-B1 | NEW PHENALKYLOXY-PHENYL DERIVATIVES | ASTRAZENECA AB (SE) | 2004-06-30 | — | — | EP | disclosed |
| US-6630509-B2 | Pharmaceutical medication associated with insulin resistance; patient with prophylaxis conditions having reduced sensitivity to insulin | ASTRAZENECA AB (SE) | 2003-10-07 | — | — | US | disclosed |