Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | GALR1 | P47211 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | GPR6 | P46095 | 4/20 | 0.32 |
| ▸ | GALR2 | O43603 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4837059 | 0.87 | MAPK1 (0.39) | MAPK1MEN1KMT2ASMN1; SMN2GALR1 | |
| SCHEMBL4829423 | 0.87 | MEN1 (0.36) | MAPK1MEN1KMT2AGALR1SLC6A2 | |
| SCHEMBL5035814 | 0.86 | GALR1 (0.44) | MAPK1MEN1KMT2AGALR1SLC6A2 | |
| SCHEMBL4837131 | 0.85 | GALR1 (0.38) | MAPK1MEN1KMT2AGALR1 | |
| SCHEMBL6207968 | 0.84 | GALR1 (0.42) | MAPK1ROCK1GALR1GALR2 | |
| SCHEMBL6820253 | 0.81 | MAPK1 (0.37) | MAPK1MEN1KMT2ASMN1; SMN2GALR1 | |
| SCHEMBL4832502 | 0.79 | GALR1 (0.45) | MAPK1GALR1GALR2 | |
| SCHEMBL5029128 | 0.78 | PKM (0.33) | KMT2AGALR1 | |
| SCHEMBL6209251 | 0.78 | MAPK1 (0.35) | MAPK1ROCK1 | |
| SCHEMBL6207668 | 0.78 | MAPK1 (0.35) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026844-A9 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS INC (US) | 2004-11-11 | — | — | WO | claimed |