Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.32 |
| ▸ | TUBB | P07437 | 2/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.32 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.32 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207668 | 0.88 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL5554463 | 0.88 | MAPK1 (0.40) | MAPK1SMN1; SMN2KMT2AGALR1ALDH1A1 | |
| SCHEMBL5031464 | 0.87 | GALR1 (0.40) | MAPK1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5553543 | 0.85 | MAPK1 (0.37) | MAPK1 | |
| SCHEMBL6207968 | 0.83 | GALR1 (0.42) | MAPK1GALR1PIK3CA | |
| SCHEMBL6818937 | 0.81 | MAPK1 (0.37) | MAPK1SMN1; SMN2MEN1KMT2AGALR1 | |
| SCHEMBL5550421 | 0.79 | MAPK1 (0.39) | MAPK1SMN1; SMN2MEN1KMT2AGALR1 | |
| SCHEMBL6428528 | 0.79 | GALR1 (0.35) | MAPK1GALR1 | |
| SCHEMBL5554034 | 0.79 | GALR1 (0.38) | MAPK1SMN1; SMN2MEN1KMT2AGALR1 | |
| SCHEMBL6607370 | 0.78 | GALR1 (0.39) | MAPK1SMN1; SMN2MEN1KMT2AGALR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026844-A9 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS INC (US) | 2004-11-11 | — | — | WO | claimed |