SCHEMBL6819014

SCHEMBL6819014

CC(C)(C)OC(=O)CCC(C#N)(C#N)CCC(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CTSK P43235 1/20 0.30
STING1 Q86WV6 1/20 0.30
AAK1 Q2M2I8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4861141 0.85 CTSK (0.31) CTSKAAK1
SCHEMBL12693593 0.84 AAK1 (0.36) CTSKSTING1AAK1
SCHEMBL6814652 0.81 CTSK (0.36) CTSK
SCHEMBL6818737 0.81 KMT2A (0.38)
SCHEMBL2485568 0.78 ALDH1A1 (0.33)
SCHEMBL4868437 0.76 CNR2 (0.31)
SCHEMBL2487231 0.75 TDP1 (0.31)
SCHEMBL4866619 0.74
SCHEMBL4866646 0.73
SCHEMBL12543691 0.73 EPHX2 (0.37) STING1AAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004020399-A1 MALONONITRILE COMPOUND AND USE THEREOF AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-03-11 WO disclosed