Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818621 | 0.95 | PIK3CA (0.37) | CRHR1 | |
| SCHEMBL6822135 | 0.85 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL6818672 | 0.82 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL6821866 | 0.82 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL6814127 | 0.81 | CRHR1 (0.37) | CRHR1 | |
| SCHEMBL6082552 | 0.80 | — | — | |
| SCHEMBL6082613 | 0.79 | — | — | |
| SCHEMBL6082618 | 0.79 | — | — | |
| SCHEMBL6814390 | 0.78 | PIK3CA (0.42) | — | |
| SCHEMBL6814575 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004031189-A1 | PYRIDINO AND PYRIMIDINO PYRAZINONES FOR TREATMENT OF ANXIETY AND DEPRESSION | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2004-04-15 | — | — | WO | disclosed |