Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | BACE1 | P56817 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819202 | 1.00 | HPGD (0.59) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL2317503 | 0.85 | KDM4E (0.58) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL2123996 | 0.84 | USP2 (0.68) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL2123998 | 0.84 | USP2 (0.68) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL2161598 | 0.84 | USP2 (0.68) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL18606600 | 0.81 | ALDH1A1 (0.52) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL6822725 | 0.81 | CA12 (0.70) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL17550790 | 0.81 | CA12 (0.70) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL6822726 | 0.81 | CA12 (0.70) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL28606462 | 0.80 | CA12 (0.60) | HPGDKDM4EALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067518-A1 | SUBSTITUTED PYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-08-12 | — | — | WO | disclosed |